Most times you see a lizard it runs off just as you get close enough, and the smaller they are, the faster they run.
Here are a few photos of the ones we saw on the Galapagos Islands where they just don't bother. I suppose they were surrounded by Iguanas, so they felt a bit more laid back. The down side was that they were so relaxed that the main danger was treading on them. However I can report that no such tragic events were recorded.
Only one was seen to move with any degree of urgency and that was crossing a bit of sun baked sand between relatively cool rock shadows.
We tended to the same behaviour when wandering shoeless, but less gracefully. Also the other lizards didn't laugh.